Biomarkers

• Main Authors: PEMBERTON CHRISTOPHER JOSEPH, RICHARDS ARTHUR MARK, NICHOLLS MICHAEL GARY, YANDLE TIMOTHY GRANT
• Format: Patent
• Language: Chinese; English
• Published: 15.08.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; TESTING; VINEGAR; WINE

The invention provides binding agents and assays for insulin signal peptide. The agents and assays are useful in methods for predicting, diagnosing, assessing or monitoring acute cardiac disorders, glucose handling disorders and diabetes in a subject. Also provided are nucleotides, polypeptides, and kits useful in the methods of the invention. 本发明提供了胰岛素信号肽的结合剂和测定法。上述结合剂和测定法可用于预测、诊断、评估或监测对象的急性心脏疾病、葡萄糖代谢障碍以及糖尿病的方法中。还提供了可用于本发明的方法中的核苷酸、多肽、以及试剂盒。