Response-surface-method-optimized extraction process for longan leaf total flavonoids

The invention discloses a response-surface-method-optimized extraction process for longan leaf total flavonoids. The extraction process is characterized in that reflux extraction is used, a Box-Behnken response surface design method is used on the basis of single factor experiment results, three fac...

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Bibliographic Details
Main Authors LIU XIANFU, LIANG JIE, TENG JIANBEI, SUN ZHENGYI, JIN QINGQING, WEI ZHIYING
Format Patent
LanguageChinese
English
Published 11.08.2017
Subjects
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:The invention discloses a response-surface-method-optimized extraction process for longan leaf total flavonoids. The extraction process is characterized in that reflux extraction is used, a Box-Behnken response surface design method is used on the basis of single factor experiment results, three factors including ethanol concentration, ethanol use amount and extraction time are used as the response variables, longan leaf total flavonoid yield is used as the response value, polynomial fitting regression is performed on the factors to obtain a regression equation, performing calculation on the regression equation to obtain the optimal extraction process conditions with the ethanol concentration being 53%, the ethanol use amount being 57mL and the reflux time being 83 minutes, and the total flavonoid extraction rate under the conditions is 15.479% which is quite close to a predicted value 15.482%. The extraction process has the advantages that the extraction process is high in extraction rate, simple, practicabl
Bibliography:Application Number: CN20171313087