Partially encapsulated waveguide based sensing chips, systems and methods of use

• Main Authors: CHANG YUN-PEI, TAN MING, DUER REUVEN, SABET LEYLA, TODD CHRISTOPHER E, SHASTRY ASHUTOSH
• Format: Patent
• Language: Chinese; English
• Published: 01.08.2017
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS; OPTICS; PHYSICS; TESTING

Optical readers and alignment tools for detecting the level of an analyte. Described herein are small, disposable partially-encapsulated sensing chips for detecting an analyte level from a fluid sample (e.g., a blood sample) having an edge of the integrated sensing chip exposed to directly expose a plurality of excitation and a collection waveguides, as well as optical readers and methods of operating them. A fluid sample maybe applied to a sensing surface of the sensing chip in the housing so that an analyte level can be optically detected. Also described are methods of sensing an analyte using these devices and systems including an optical detector. 用于检测分析物水平的光学读取器和对准工具。本文描述种用于从流体样品(例如血液样品)检测分析物水平的小型的、次性部分封装的感测芯片，其具有暴露的以直接暴露多个激励波导和收集波导的集成感测芯片的边缘，以及光学读取器，以及操作它们的方法。流体样品可施加至壳体中的感测芯片的感测表面，使得可光学地检测分析物水平。还描述种使用这些设备和包括光学检测器的系统的感测分析物的方法。