Dendrobium officinale polysaccharide with anti-tumor and anti-oxidation functions

• Main Authors: MAO ZHENGHUA, LIN PEILI
• Format: Patent
• Language: Chinese; English
• Published: 21.07.2017
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention discloses a dendrobium officinale polysaccharide with anti-tumor and anti-oxidation functions. The dendrobium officinale polysaccharide is sulfated modification dendrobium officinale polysaccharide SDOS-2, the molecular weight of the sulfated modification dendrobium officinale polysaccharide SDOS-2 is 9.53*104Da, the sulfate radical content is 14.70%, substitution degree is 1.29, and the sulfated modification dendrobium officinale polysaccharide SDOS-2 comprises glucose, mannose, galactose, glucuronic acid, arabinose and galacturonic acid. The dendrobium officinale polysaccharide has the advantages that the prepared sulfated modification dendrobium officinale polysaccharide SDOS-2 exceeds positive control ascorbic acid in the aspect of removing an IC50 value of DPPH (diphenyl picrylhydrazyl) and O2-free radical and has a certain growth-promoting functions on cells, remarkable anti-tumor and anti-oxidation functions and quite wide market application prospect. 种兼具抗肿瘤和抗氧化作用的铁皮石斛多糖，该铁皮石斛多糖为硫酸化修饰的铁皮石