Aescin A liposome gel and a preparing method thereof
Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a seco...
Saved in:
Main Authors | , , , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
14.07.2017
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a second step of preparing the liposome gel. Compared with common gel agents, the liposome gel has better transdermal absorption effects, has a controlled release function, and can be slowly released at a certain speed, thus forming a constant plasma concentration of a medicine in skin and prolonging the treatment time of a medicine. The aescin A liposome gel also can reduce the occurrence rate of skin irritative reactions.
本发明公开了种七叶皂苷A脂质体凝胶,它由七叶皂苷A、大豆磷脂、胆固醇、卡波姆、三乙醇胺、EDTA·2Na、薄荷脑等成分组成。本发明还公开了制备方法,包括制备脂质体和制备脂质体凝胶两个步骤。与普通凝胶剂相比,本发明公开的脂质体凝胶不仅具有更好的透皮吸收效果,而且具有缓控释作用,能够以定速率缓慢释放,从而在皮肤内形成恒定的血药浓度,有利于延长药物的治疗时间,本发明还能减少皮肤刺激反应的发生率。 |
---|---|
AbstractList | Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a second step of preparing the liposome gel. Compared with common gel agents, the liposome gel has better transdermal absorption effects, has a controlled release function, and can be slowly released at a certain speed, thus forming a constant plasma concentration of a medicine in skin and prolonging the treatment time of a medicine. The aescin A liposome gel also can reduce the occurrence rate of skin irritative reactions.
本发明公开了种七叶皂苷A脂质体凝胶,它由七叶皂苷A、大豆磷脂、胆固醇、卡波姆、三乙醇胺、EDTA·2Na、薄荷脑等成分组成。本发明还公开了制备方法,包括制备脂质体和制备脂质体凝胶两个步骤。与普通凝胶剂相比,本发明公开的脂质体凝胶不仅具有更好的透皮吸收效果,而且具有缓控释作用,能够以定速率缓慢释放,从而在皮肤内形成恒定的血药浓度,有利于延长药物的治疗时间,本发明还能减少皮肤刺激反应的发生率。 |
Author | SHI ZHAOHUA GUAN XIAOYU ZHANG XIAOCUN LI QUN YE LICHUN DU WENJIE |
Author_xml | – fullname: GUAN XIAOYU – fullname: ZHANG XIAOCUN – fullname: SHI ZHAOHUA – fullname: LI QUN – fullname: YE LICHUN – fullname: DU WENJIE |
BookMark | eNrjYmDJy89L5WQwcUwtTs7MU3BUyMksyC_Oz01VSE_NUUjMS1FIVCgoSi1ILMrMS1fITS3JyE9RKMlILUrNT-NhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoYGZpYmxsbGlo7GxKgBANbDLeM |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | 七叶皂苷A脂质体凝胶及其制备方法 |
ExternalDocumentID | CN106943339A |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_CN106943339A3 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 16:58:18 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | Chinese English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_CN106943339A3 |
Notes | Application Number: CN20171212793 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170714&DB=EPODOC&CC=CN&NR=106943339A |
ParticipantIDs | epo_espacenet_CN106943339A |
PublicationCentury | 2000 |
PublicationDate | 20170714 |
PublicationDateYYYYMMDD | 2017-07-14 |
PublicationDate_xml | – month: 07 year: 2017 text: 20170714 day: 14 |
PublicationDecade | 2010 |
PublicationYear | 2017 |
RelatedCompanies | WUHAN AIMIN PHARMACEUTICAL CO., LTD |
RelatedCompanies_xml | – name: WUHAN AIMIN PHARMACEUTICAL CO., LTD |
Score | 3.2169542 |
Snippet | Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na,... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | Aescin A liposome gel and a preparing method thereof |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170714&DB=EPODOC&locale=&CC=CN&NR=106943339A |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fS8MwED7mFPVNp6LzBxGkb0XbpO36UKRLV4awbsiUvY22S-dktmWtCP71XmrnfNG3kMAlObjcl0u-O4AbihhDj21LxjUMldn6TEXc3FHNSDONRCBGoZLgPAjM_hN7mBiTBryuuTBVntCPKjkiWlSM9l5W53W-CWJ51d_K4jZaYFd2748dT6lvx5ol-TiK13V6o6E35ArnDg-U4BGxrmkzSqntbsG2hNEyz37vuStZKflvl-IfwM4IpaXlITQ-X1qwx9eV11qwO6gfvLFZ215xBMwV6K5S4pLlIs-K7E2QuViSMJ2RkOQrIcsJpnPyXRKaSFwnsuQYrv3emPdVnH76s9cpDzYrpSfQTLNUnAIJ9UijkWVGd1rMkpB1EptZVqLjdSS2Q6adQftvOe3_Bs9hX-pNhis1dgHNcvUuLtHPltFVpaAvV_Z_vg |
link.rule.ids | 230,309,786,891,25594,76903 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT8IwEL8gGvFNUaP4VROzt0W3dht7IGZ0kKkwiEHDG9lGhxjcFpgx8a_3OkF80bemTa4fyfV-d-3vDuCKIsbQI9uScQ1DZbY-VhE311Uz1EwjFohRqCQ4d33Te2L3Q2NYgtcVF6bIE_pRJEdEjYpQ3_Pivs7WQSy3-Fu5uA6n2JXetgcNV1l6x5ol-TiK22y0-j23xxXOG9xX_EfEuqbNKKW2swGbFrqEhav03JSslOy3SWnvwlYfpSX5HpQ-X6pQ4avKa1XY7i4fvLG51L3FPjBHoLlKiENm0yxdpG-CTMSMBMmYBCSbC1lOMJmQ75LQROI6kcYHcNluDbin4vSjn72OuL9eKT2EcpIm4ghIoIcaDS0zvNEiFgesHtvMsmId3ZHIDph2DLW_5dT-G7yAijfodkadO__hBHbkGcrQpcZOoZzP38UZ2tw8PC8O6wt1zIKo |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Aescin+A+liposome+gel+and+a+preparing+method+thereof&rft.inventor=GUAN+XIAOYU&rft.inventor=ZHANG+XIAOCUN&rft.inventor=SHI+ZHAOHUA&rft.inventor=LI+QUN&rft.inventor=YE+LICHUN&rft.inventor=DU+WENJIE&rft.date=2017-07-14&rft.externalDBID=A&rft.externalDocID=CN106943339A |