Aescin A liposome gel and a preparing method thereof
Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a seco...
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Main Authors | , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
14.07.2017
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Subjects | |
Online Access | Get full text |
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Summary: | Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a second step of preparing the liposome gel. Compared with common gel agents, the liposome gel has better transdermal absorption effects, has a controlled release function, and can be slowly released at a certain speed, thus forming a constant plasma concentration of a medicine in skin and prolonging the treatment time of a medicine. The aescin A liposome gel also can reduce the occurrence rate of skin irritative reactions.
本发明公开了种七叶皂苷A脂质体凝胶,它由七叶皂苷A、大豆磷脂、胆固醇、卡波姆、三乙醇胺、EDTA·2Na、薄荷脑等成分组成。本发明还公开了制备方法,包括制备脂质体和制备脂质体凝胶两个步骤。与普通凝胶剂相比,本发明公开的脂质体凝胶不仅具有更好的透皮吸收效果,而且具有缓控释作用,能够以定速率缓慢释放,从而在皮肤内形成恒定的血药浓度,有利于延长药物的治疗时间,本发明还能减少皮肤刺激反应的发生率。 |
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Bibliography: | Application Number: CN20171212793 |