Preparation method for reprogramming somatic cells into neural stem cells by microRNA, and application of neural stem cells

• Main Author: WANG YUESI
• Format: Patent
• Language: Chinese; English
• Published: 11.07.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention provides a method for induced transdifferentiation of somatic cells into neural stem cells, and an application of the neural stem cells, and concretely relates to neural stem cells with high yield, good pluripotency and good passage stability, formed through inducing human fibroblasts,...