Oral drug composition for vascular endothelial growth factor inhibitor

• Main Authors: WANG SHULI, CHEN LIYING, HE GUANGJIE, SUN LIANG, LI JING, YANG XINYI, HU XIAOYUN
• Format: Patent
• Language: Chinese; English
• Published: 27.06.2017
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention belongs to the medical field, particularly relates to an oral drug composition for inhibiting salt of a compound of formula I (shown in the description) of a VEGF, pharmaceutical use of the oral drug composition and a pharmaceutical preparation and particularly aims at treatment of tumors and angiogenesis. The invention further relates to a synthetic method of the compound. 本发明属于医药领域，特别涉及抑制VEGF的式Ⅰ化合物的盐口服药物组合物，在药物上的用途和药用制剂，特别是针对肿瘤、血管新生的治疗。本发明也涉及该化合物的合成方法。