Preparation method of tablet containing phentermine hydrochloride-topiramate

The invention provides a preparation method of a tablet containing phentermine hydrochloride-topiramate. The preparation method comprises the following steps: preparing a rapid-release part, preparing a slow-release part, and carrying out tabletting. For the tablet, topiramate is taken as the slow-r...

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Bibliographic Details
Main Authors YAN LIQUN, DENG RUOHAN, AN SHIZHI, ZHOU SHIWANG
Format Patent
LanguageChinese
English
Published 23.06.2017
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Summary:The invention provides a preparation method of a tablet containing phentermine hydrochloride-topiramate. The preparation method comprises the following steps: preparing a rapid-release part, preparing a slow-release part, and carrying out tabletting. For the tablet, topiramate is taken as the slow-release part, and phentermine hydrochloride is taken as the rapid-release part. With the adoption of the preparation method, the problems that for the common controlled-release pellets, the process is complicated and the control is difficult during large-scale production are solved, and the preparation method provided by the invention is simple and is suitable for industrial mass production, thus having very good application prospects. 本发明提供了种含盐酸芬特明-托吡酯片剂的制备方法,包括:速释部分、缓释部分、压片等步骤:该片剂其中托吡酯为缓释部分,盐酸芬特明为速释部分。本发明解决了般缓释微丸工艺复杂且放大生产中不易控制的问题,本产品制备方法简单,适宜于工业化大生产,具有很好的应用前景。
Bibliography:Application Number: CN20151936285