Rhizopus oryzae solid state fermentation extractive, preparation method and anticancer application thereof

• Main Authors: JI BAOPING, YANG DANHUA, ZHOU FENG, ZHAO LIANG, WU WEI, JIN XIAOLU, ZENG XIANG, CAI SHENGBAO
• Format: Patent
• Language: Chinese; English
• Published: 20.06.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the technical field of fermentation and specifically relates to a rhizopus oryzae solid state fermentation extractive, a preparation method and an anticancer effect thereof. The method comprises the following steps: taking grains as substrates; performing rhizopus oryzae solid state fermentation, and then extracting a neutral organic solvent, thereby acquiring a product. The product has the obvious functions of selectively killing cancer cells, accelerating cancer cell apoptosis and restraining the growth of in vivo tumors. The longest absorption wavelength of the product is within the scope of 180nm-400nm. The key point of the invention is to ferment and extract the grains, so that the nutritive value and health efficacy of the grains are promoted and utilized. The product has an obvious anticancer effect and can achieve the anticancer effect in the fields, such as, medical biology, health care products and drugs. 本发明属于发酵技术领域，具体涉及种米根霉发酵谷物产物提取物、制备方法及其产生的抗癌功效：以谷物为底物，采用米根霉固态发酵后，经中性有机溶剂萃