Preparation method of escitalopram oxalate impurities
The application of the invention provides a brand-new preparation method of (R)-4-(dimethylamino)-1-(1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)-butyl-1-ketone to provide a basis for qualitative and quantitative analysis of impurity profiles in escitalopram oxalate...
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Main Authors | , , |
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Format | Patent |
Language | Chinese English |
Published |
09.06.2017
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Subjects | |
Online Access | Get full text |
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Summary: | The application of the invention provides a brand-new preparation method of (R)-4-(dimethylamino)-1-(1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)-butyl-1-ketone to provide a basis for qualitative and quantitative analysis of impurity profiles in escitalopram oxalate finished products, thereby having a significant role in quality control of escitalopram oxalate and being capable of promoting the safe use of depressive patients.
本申请提供了草酸艾司西酞普兰工艺杂质()-4-(二甲氨基)-1-(1-(3-(二甲氨基)丙基)-1-(4-氟苯基)-1,3-二氢异苯并呋喃-5-基)-丁基-1-酮的种全新的制备方法,为定性、定量分析草酸艾司西酞普兰成品中杂质情况提供依据,对草酸艾司西酞普兰的质量控制具有重大作用,能够促进抑郁病患安全用药。 |
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Bibliography: | Application Number: CN2017172509 |