Preparation method of escitalopram oxalate impurities

The application of the invention provides a brand-new preparation method of (R)-4-(dimethylamino)-1-(1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)-butyl-1-ketone to provide a basis for qualitative and quantitative analysis of impurity profiles in escitalopram oxalate...

Full description

Saved in:
Bibliographic Details
Main Authors ZHAO YUNPING, WANG NA, ZHAO GUOLEI
Format Patent
LanguageChinese
English
Published 09.06.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The application of the invention provides a brand-new preparation method of (R)-4-(dimethylamino)-1-(1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)-butyl-1-ketone to provide a basis for qualitative and quantitative analysis of impurity profiles in escitalopram oxalate finished products, thereby having a significant role in quality control of escitalopram oxalate and being capable of promoting the safe use of depressive patients. 本申请提供了草酸艾司西酞普兰工艺杂质()-4-(二甲氨基)-1-(1-(3-(二甲氨基)丙基)-1-(4-氟苯基)-1,3-二氢异苯并呋喃-5-基)-丁基-1-酮的种全新的制备方法，为定性、定量分析草酸艾司西酞普兰成品中杂质情况提供依据，对草酸艾司西酞普兰的质量控制具有重大作用，能够促进抑郁病患安全用药。
Bibliography:Application Number: CN2017172509