A novel compound isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient, the composition comprising the same for preventing or treating allergy disease, inflammatory disease, asthma or chronic obstructive pulmonary disease and the use thereof

• Main Authors: OH SEI-RYANG, LEE YONGNAM, YOO JI-SEOK, AHN KYUNG-SEOP, SONG HYUK-HWAN, LEE SU UI, SHIN DAE-HEE, RYOO BYUNG-HWAN, SHIN IN-SIK, LEE HYEONG-KYU, RYU HYUNG WON
• Format: Patent
• Language: Chinese; English
• Published: 31.05.2017
• Subjects: CHEMISTRY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a novel methanocyclopenta[e][1,3]dioxepin-7-yl 3,4-dihydroxybenzoate derivative (KS534) represented below as the Chemical Formula 1, the pharmaceutically acceptable salt or solvates thereof, a composition comprising the same as an active ingredient for preventing or treating allergic disease, inflammatory disease, asthma or chronic obstructive pulmonary disease (COPD) and the use thereof. 本发明涉及通过化学式(1)表示的新的亚甲基桥环戊二烯并[e][1,3]二氧杂环庚烯-7-基3,4-二羟基苯甲酸酯衍生物(KS534)、其药学上可接受的盐或溶剂化物，用于预防或治疗变应性疾病、炎性疾病、哮喘或慢性阻塞性肺病(COPD)的包含该化合物作为活性成分的组合物及它们的用途。式(1)：