Modified host cells and uses thereof

Described herein are modified host cells useful in the production of bioconjugates that can be used to vaccinate subjects against infection with Pseudomonas. The genomes of the modified host cells described herein comprise genes that encode proteins involved in glyosylation of proteins as well as ge...

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Main Authors KOWARIK MICHAEL, FERON CHRISTIANE MARIE-PAULE SIMONE JEANNE, KEMMLER STEFAN J, QUEBATTE JULIEN L
Format Patent
LanguageChinese
English
Published 31.05.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Described herein are modified host cells useful in the production of bioconjugates that can be used to vaccinate subjects against infection with Pseudomonas. The genomes of the modified host cells described herein comprise genes that encode proteins involved in glyosylation of proteins as well as genes specific to the production of Pseudomonas-specific antigens. 本文描述了可用于生产生物结合物的经修饰的宿主细胞，所述生物结合物可被用于为个体接种抗假单胞菌感染的疫苗。本文所述的经修饰的宿主细胞的基因组包含编码涉及蛋白质糖基化的蛋白质的基因以及针对假单胞菌特异性抗原的生产的基因。
Bibliography:Application Number: CN201480079804