Method for treating drug resistant cancer

Provided is a method for treating a subject with a cancer resistant to a chemotherapeutic drug comprising administering to said subject a therapeutically effective amount of prochlorperazine or its analog or metabolite, or a pharmaceutically acceptable salt thereof, in combination of the chemotherap...

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Bibliographic Details
Main Authors CHANG PETER MU-HSIN, WU CHUN-HUNG, CHEN KUAN-YU, HUANG CHI-YING, CHENG TAI-SHAN, YU CHENG-HAO
Format Patent
LanguageChinese
English
Published 31.05.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided is a method for treating a subject with a cancer resistant to a chemotherapeutic drug comprising administering to said subject a therapeutically effective amount of prochlorperazine or its analog or metabolite, or a pharmaceutically acceptable salt thereof, in combination of the chemotherapeutic drug. Also provided is a method for preventing cancer metastasis with the combination of prochlorperazine in combination of a chemotherapeutic drug. 本发明涉及种治疗具有对化疗药物具抗药性的癌症的个体的方法，包含对所述个体组合投予治疗有效量的普洛陪拉幸(prochlorperazine)或其类似物或代谢物、或其医药上可接受盐类，和所述化疗药物。本发明亦涉及种以普洛陪拉幸和化疗药物组合的组合预防癌症转移的方法。
Bibliography:Application Number: CN201580035554