One-pot method for preparing hydrophilic phytosterol/stanol derivative

• Main Authors: HE WENSEN, WANG HUIHUI, ZHANG YILU, CUI DANDAN, LIU YU
• Format: Patent
• Language: Chinese; English
• Published: 31.05.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; SPIRITS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; VINEGAR; WINE

The invention discloses a one-pot method for preparing a hydrophilic phytosterol/stanol derivative, and belongs to the technical fields of food, cosmetics, medicine and chemical engineering. Phytosterol/stanol and diacid or diacid anhydride react for a period of time under the action of ionic liquid to generate the high-purity intermediate product phytosterol/stanol diacid monoester; a hydrophilic modifier is directly added to the reaction system for further reaction without separating the intermediate product, so that a high-purity hydrophilic phytosterol/stanol derivative is prepared. The hydrophilic phytosterol/stanol derivative with purity over 95% can be obtained through extraction separation. The two phases of esterification reaction are conducted in one pot, technological operation is simple, usage and separation of a solvent are reduced, the technological process is short, and energy consumption is reduced. The obtained hydrophilic phytosterol/stanol derivative is high in purity, high in yield and low