Method and apparatus for suprachoroidal administration of therapeutic agent

• Main Authors: BRUEHWILER MICHEL G, GRUBBS NATHAN D, KEANE MICHAEL F, OBERKIRCHER BRENDAN J, YASEVAC DANIEL J, SOFFER LEAH R, PRICE DANIEL W, KHAN ISAAC J, SOKHANVAR SAEED, RIEMANN CHRISTOPHER D, KO BENJAMIN L
• Format: Patent
• Language: Chinese; English
• Published: 17.05.2017
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

An apparatus (10) for delivering therapeutic agent to an eye comprises a body (40), a cannula (20), a hollow needle (30), and an actuation assembly (60). The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy. 本发明公开了种用于将治疗剂递送到眼的设备(10)，该设备10包括主体(40)、插管(20)、中空针(30)和致动组件(60)。该插管从主体朝远侧延伸并且尺寸和构造使得其能够插入患者眼的脉络膜和巩膜之间。该致动组件能够操作以相