Method for constructing quinoline compound by means of functionalization of organic antimony catalyzed C-H bond

• Main Authors: PENG YAO, YIN SHUANGFENG, LEI JIAN, QIU RENHUA
• Format: Patent
• Language: Chinese; English
• Published: 17.05.2017
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention aims at developing a novel method for preparing a quinoline compound in a manner of high conversion rate and high yield from organic antimony frustrated lewis pair catalyst by means of C-H bond functionalization of imine and unsaturated hydrocarbon at air atmosphere. As air is utilized as an oxidizing agent, the method has the advantages of mild reaction condition, green and environment-friendly preparation process, simple catalyzing system, low cost, excellent conversion rate and yield of target product and capability of recycling catalyst, and has a favorable industrial application prospect. 本发明公开了本发明的目的是开发种在空气氛围下，利用有机锑受阻路易斯酸碱对催化剂，通过亚胺与不饱和烃的C-H键官能团化，高转化率和高产率地制备喹啉类化合物的新方法；该方法反应条件温和，利用空气作为氧化剂，制备过程绿色环保，催化体系简单，成本低，目标产物的转换率和产率优越，催化剂可回收再利用，具有良好的工业应用前景。