组蛋白脱甲基酶抑制剂

本公开内容大体上涉及用于治疗癌症和肿瘤病的组合物和方法。本文提供了被取代的吡啶衍生物化合物和包含所述化合物的药物组合物。主题化合物和组合物对于抑制组蛋白脱甲基酶是有用的。此外，主题化合物和组合物对于治疗癌症是有用的，所述癌症为例如前列腺癌、乳腺癌、膀胱癌、肺癌和/或黑色素瘤及类似癌症。 The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine de...

Full description

Saved in:
Bibliographic Details
Format Patent
LanguageChinese
Published 08.09.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:本公开内容大体上涉及用于治疗癌症和肿瘤病的组合物和方法。本文提供了被取代的吡啶衍生物化合物和包含所述化合物的药物组合物。主题化合物和组合物对于抑制组蛋白脱甲基酶是有用的。此外，主题化合物和组合物对于治疗癌症是有用的，所述癌症为例如前列腺癌、乳腺癌、膀胱癌、肺癌和/或黑色素瘤及类似癌症。 The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
Bibliography:Application Number: CN20158045921