Medicine for treating colitis and application of compound to preparation of medicine for treating colitis

• Main Author: TIAN FENGXIANG
• Format: Patent
• Language: Chinese; English
• Published: 29.03.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a medicine for treating colitis. The medicine comprises a compound shown in the following formula, and the medicine can be a stereoisomer of the compound, or a geometrical isomer of the compound, or a tautomer of the compound, or pharmaceutically acceptable salt of the compound, or a pharmaceutically acceptable carrier, or a pharmaceutically acceptable excipient, or a pharmaceutically acceptable diluent, or a pharmaceutically acceptable adjuvant, or a pharmaceutically acceptable medium or pharmaceutically acceptable combinations of the carrier, the excipient, the diluent, the adjuvant and the medium. Please see the specifications for the formula, R1 is F, or Cl, or Br or I, and R2 is F, or Cl, or Br or I. The medicine can relieve the tissue pathological change states, remarkably lower MPO activity and the content of TNF-alpha and IL-beta, and reduce releasing of inflammatory factors, and the medicine can be hopefully developed into a novel medicine for clinic use. 本发明涉及种治疗结肠炎的药物，所述药物包