3D printed radix notoginseng total saponins orally disintegrating tablet and preparation method thereof

• Main Authors: CHEN HUOJI, ZHU HONGXIA, LIU QIANG, RUAN SHIFA, XIANG SHIJIAN, WENG LIDONG, AN BAICHAO, HONG JUNHUI, CAO SIWEI
• Format: Patent
• Language: Chinese; English
• Published: 22.03.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a 3D printed radix notoginseng total saponins orally disintegrating tablet and a preparation method thereof. The preparation method comprises the steps of uniformly mixing, in percentage by weight, 10-30% of radix notoginseng total saponins, 15-35% of microcrystalline cellulose, 30-50% of mannitol, 10-15% of povidone, 0-0.5% of micropowder silica gel and 0-0.5% of a flavoring agent, and putting a mixture into a powder box; putting an adhesive into an ink box; performing modeling according to preset parameters, and importing a model to a control system of a 3D printing and fast-forming machine; outputting an instruction by the control system to print a radix notoginseng total saponins orally disintegrating tablet; and after a dispersible tablet is adhered and dried, taking out the tablet to obtain the 3D printed radix notoginseng total saponins orally disintegrating tablet. According to the 3D printed radix notoginseng total saponins orally disintegrating tablet and the preparation meth