3-substituted 2-amino-indole derivatives

• Main Authors: BARKER GREGORY, GOLDBY ANNE, FARNABY WILLIAM, WILLEMS HENRIETTE, HARRISON DAVID, DOWNHAM ROBERT, DAVENPORT RICHARD, HANNAH DUNCAN
• Format: Patent
• Language: Chinese; English
• Published: 08.03.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides compounds of formula (I) (Formula (I)) and pharmaceutically acceptable salts thereof, wherein Q, X% X4,X5 X6, X7,R1, R2, R3 and R8 are as defined in the specification, processes for the preparation of such compounds, pharmaceutical compositions containing them and the use of such compounds in therapy. 本发明提供了如式(I)所示的化合物(式(I))及其药学可接受的盐，其中Q、X％X、X、X、X、R、R、R和R如说明书所定义，所述化合物的制备方法、包含它们的药物组合物以及所述化合物在治疗中的应用。