Application of polypeptide complex as GLP-1 drug carrier, method and fusion protein complex

The invention provides an application of a polypeptide complex based on a Titin-Telethonin beta-pleated sheet structure as a GLP-1 drug carrier, a method and a fusion protein complex; while polypeptides or protein drugs can maintain activity, the half-life period is effectively prolonged, and the po...

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Bibliographic Details
Main Authors SUN JIBIN, ZOU PEIJIAN, SU WENCHENG, TAN HUANBO
Format Patent
LanguageChinese
English
Published 15.02.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides an application of a polypeptide complex based on a Titin-Telethonin beta-pleated sheet structure as a GLP-1 drug carrier, a method and a fusion protein complex; while polypeptides or protein drugs can maintain activity, the half-life period is effectively prolonged, and the polypeptide complex is better applied in clinic. 本发明创造提供了基于Titin-Telethonin β-折叠片结构的多肽复合物作为GLP-1药物载体的应用、方法及其融合蛋白复合物，能够使多肽或者蛋白质类药物在保持活性的同时，有效延长半衰期，更好地在临床上得到应用。
Bibliography:Application Number: CN201610810446