Application of polyoxymethylflavone, polyoxymethylflavone composition and polyoxymethylflavone preparation for prevention or treatment of hyperlipidemia

• Main Authors: LIU EHU, XIE ZHISHEN, XIAO PINGTING
• Format: Patent
• Language: Chinese; English
• Published: 15.02.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses application of polyoxymethylflavone, a polyoxymethylflavone composition and a polyoxymethylflavone preparation for prevention or treatment of hyperlipidemia. The active ingredient of a drug for the prevention or treatment of the hyperlipidemia comprises polyoxymethylflavone, wherein the polyoxymethylflavone refers to 3,5,6,7,8,3',4'-heptamethoxyflavones, and the active ingredient further comprises pharmaceutically acceptable carriers or excipients so as to be prepared into a pharmaceutically acceptable dosage form. The high level of either of the total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-c) of plasma can cause the hyperlipidemia. The invention confirms that 3,5,6,7,8,3',4'-heptamethoxyflavones (HMF) can significantly reduce the levels of the TG, the TC and the LDL-c, significantly increase the level of HDL-C in the plasma, and prevent or treat the hyperlipidemia. 本发明公开了种多甲氧基黄酮、组合物及其制剂在预防或治疗高脂血症中的应用，该用于预防或治疗高脂血症的药物的活性成分包括多甲氧基黄酮，所述多甲氧基黄酮为3,5,6