Method for extracting mono-ammonium glycyrrhizinate from glycyrrhizic acid

The invention discloses a method for extracting mono-ammonium glycyrrhizinate from glycyrrhizic acid. The method comprises the steps that 1, 90% ethyl alcohol is utilized for repeated extraction at the temperature of 70 DEG C, filtration is carried out through a plate-and-frame filter press to obtai...

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Bibliographic Details
Main Authors LIU JIA, JI HAO, KONG FANBO, ZHOU HUIMIN, YU YANYAN, DOU CHANGQING, KAN JIANWEI
Format Patent
LanguageChinese
English
Published 12.10.2016
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
STEROIDS
SUGARS
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Summary:The invention discloses a method for extracting mono-ammonium glycyrrhizinate from glycyrrhizic acid. The method comprises the steps that 1, 90% ethyl alcohol is utilized for repeated extraction at the temperature of 70 DEG C, filtration is carried out through a plate-and-frame filter press to obtain an extracting solution; 2, after ethyl alcohol is removed through distillation, liquid nitrogen is introduced for neutralization and crystallization, the pH value is controlled to be 8.9-9.2, and centrifugal drying is carried out to obtain mono-ammonium glycyrrhizinate crude product; 3, 90% ethyl alcohol and medicinal active carbon are used for extraction and decolorization at the temperature of 80 DEG C, cooling, sedimentation and filtration are carried out, and mono-ammonium glycyrrhizinate wet product; 4, drying and smashing are carried out, and mono-ammonium glycyrrhizinate is obtained. By strictly controlling the variety and concentration of the extracting agent and extracting temperature in the extracting p
Bibliography:Application Number: CN20161413725