Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine

A combination of a 4-anilino-3-cyanoquinoline compound (e.g. HKI-272, SKI-606, EKB-569) and a capecitabine compound in the treatment of a neoplasm is provided. Regimens, kits, and methods for treatment of neoplasm, including breast cancer including metastatic breast cancer, and lung cancer, using th...

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Bibliographic Details
Main Authors WANG KENNETH, QUINN SUSAN, ZACHARCHUK CHARLES, BINLICH FLORENCE
Format Patent
LanguageChinese
English
Published 28.09.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A combination of a 4-anilino-3-cyanoquinoline compound (e.g. HKI-272, SKI-606, EKB-569) and a capecitabine compound in the treatment of a neoplasm is provided. Regimens, kits, and methods for treatment of neoplasm, including breast cancer including metastatic breast cancer, and lung cancer, using this combination, optionally in combination with other anti-neoplastic agents, or immune modulators are also described. 提供了治疗肿瘤的4-苯胺基-3-氰基喹啉化合物(例如，HKI-272、SKI-606、EKB-569)和卡培他滨化合物的组合。也描述了使用该组合并任选与其他抗肿瘤剂或免疫调节剂组合，治疗肿瘤包括乳腺癌(包括转移性乳腺癌)和肺癌的用药方案、试剂盒和方法。
Bibliography:Application Number: CN201610390375