Method for producing indoline compound

• Main Authors: SADO TATSUNORI, KASAI ATSUYUKI, FUKUHARA YASUAKI, TAKATA KATSUNORI, UEMURA MASATO, MOTOYAMA TAKAHIRO
• Format: Patent
• Language: Chinese; English
• Published: 21.09.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Provided is a method for producing a compound represented by formula (6), the method including a step of mixing a compound represented by formula (4) with a compound represented by formula (5) so as to generate a salt of the compound represented by formula (4) and the compound represented by formula (5), and a step of deprotecting the protecting group P1 on the salt. (In the formulae, P1 denotes a protecting group and P2 denotes a protecting group.) 本发明提供种式(6)所示的化合物的制造方法，其包括：将式(4)所示的化合物和式(5)所示的化合物混合，从而生成包含式(4)所示的化合物和式(5)所示的化合物的盐的工序；和使所述盐的保护基P脱保护的工序。式中，P表示保护基，P表示保护基。