种合成氯甲基-1,1,1,3,3,3-六氟异丙基醚的方法

• Format: Patent
• Language: Chinese
• Published: 30.10.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

本发明公开了种合成氯甲基-1,1,1,3,3,3-六氟异丙基醚的方法，该方法包括：、向高压反应釜中加入六氟异丙醇和多聚甲醛，搅拌均匀后向所述高压反应釜中加入无水三氯化铝，控制高压反应釜内的温度为0℃～50℃，然后通入二氧化碳气体，通气结束后保温搅拌反应，二氧化碳气体的通入量为使二氧化碳呈液态或超临界态；二、排出二氧化碳，将反应物料用盐酸溶解，分出有机层，用水洗涤有机层，得到氯甲基-1,1,1,3,3,3-六氟异丙基醚。本发明以液态或超临界态二氧化碳为溶剂，有利于搅拌，使反应进行的比较完全，且容易和产物分离,省去了复杂的后处理过程，产物收率达到90％以上，纯度达到98％以上。 The invention discloses a method for synthesizing chloromethy-1,1,1,3,3,3-hexafluoroisopropyl ether. The method includes the steps that 1, hexafluoroisopropanol and paraformaldehyde are added to a high-pressure reaction kettle, anhydrous aluminium trichloride is added to the high-pressure reaction kettle after even stirring, the temperature in the high-pressure reaction kettle is controlled to be 0-50 DEG C, then carbon dioxide gas is led to the kettle, heat-preservation stirring reaction is performed after gas leading is completed, and the adding amount of the carbon dioxide gas is used for making carbon dioxide in a liquid or supercritical state; 2, the carbon dioxide is discharged out, the reaction material is dissolved