Green synthesis method of acetal-type or ketal-type compound

• Main Authors: Xu Zhuowei, Ping Yisi, Liu Liangliang, Cheng Zhifei
• Format: Patent
• Language: Chinese; English
• Published: 17.08.2016
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a green synthesis method of an acetal-type or ketal-type compound. A carbonyl compound is used as a raw material, a hydrogen-loaded compound is used as a catalyst, then an alcohol substance is added, a reaction is performed to generate the acetal-type or ketal-type compound. The synthesis method is simple and convenient, is high in conversion rate and yield, is safe and stable, has low toxicity and is easy to operate; the used catalyst is simple to prepare, and is cheap and easy to obtain; the reaction process is mild and efficient; the product is easy to separate and purify; the green synthesis method has a wide substrate application range, can be used for synthesizing acetal and ketal spices, and has potential industrial application value. 本发明公开了种缩醛或缩酮类化合物的绿色合成方法，是以羰基化合物为原料，以载氢化合物为催化剂，再加入醇类物质，反应生成缩醛或缩酮类化合物。该合成方法简便，转化率和收率较高，安全稳定，毒性低，易于操作；使用的催化剂制备简单、廉价易得；反应过程温和高效，产物易分离纯化，具有广泛的底物适用范围，可用于缩醛和缩酮香料的合成，具有潜在工业应用价值。