Synthesis of a macrocyclic HCV NS3 inhibiting tripeptide

The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I. 本公开提供用于制备可用作抗病毒剂的式...

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Bibliographic Details
Main Authors Littke Adam, Shapiro Nathan, Karki Kapil Kumar, Seng Pamela, Siegel Dustin, Tang Donald, Ross Bruce, Yu Lawrence, Keaton Katie Ann, Cagulada Amy, Levins Chris, Chan Johann, Chan Lina, Martinez Ruben, Tripp Jonathan, Sangi Michael, Reynolds Troy, Kondapally Sudha, Schrier Adam J, Taylor James G, Colby Denise A, Pcion Dominika, Kato Darryl, Waltman Andrew W?
Format Patent
LanguageChinese
English
Published 10.08.2016
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I. 本公开提供用于制备可用作抗病毒剂的式I的化合物的方法。本公开还提供作为式I化合物的合成中间体的化合物和用于制备该化合物的方法。
Bibliography:Application Number: CN201480070017