修饰的治疗剂及其组合物

本发明提供了用于延长治疗剂的半衰期的方法和组合物。可将一个或多个半衰期延长部分附接至治疗剂，由此延长该治疗剂的半衰期。包含一个或多个附接至治疗剂的半衰期延长部分的修饰的治疗剂(mTA)可用于治疗有需要的受试者的疾病或状况。 Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending...

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Bibliographic Details
Format Patent
LanguageChinese
Published 10.10.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:本发明提供了用于延长治疗剂的半衰期的方法和组合物。可将一个或多个半衰期延长部分附接至治疗剂，由此延长该治疗剂的半衰期。包含一个或多个附接至治疗剂的半衰期延长部分的修饰的治疗剂(mTA)可用于治疗有需要的受试者的疾病或状况。 Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof.
Bibliography:Application Number: CN201480062386