Novel chemical compounds (variants) and the use thereof to treat oncological diseases

The invention relates to novel chemical compounds of general formula I, in which LA, LB, LC, cycle A, cycle B, RA, RB, RC, RD, RE and RF have the values indicated in the description, and which are protein kinase inhibitors. The invention also relates to pharmaceutical compositions containing said co...

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Main Authors STROILOV VIKTOR SERGEEVICH, ZEIFMAN ALEKSEY ALEXANDROVICH, NOVIKOV FEDOR NIKOLAEVICH, CHILOV GERMES GRIGORIEVICH, STROGANOV OLEG VALENTINOVICH, TITOV ILYA YURIEVICH
Format Patent
LanguageChinese
English
Published 13.04.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel chemical compounds of general formula I, in which LA, LB, LC, cycle A, cycle B, RA, RB, RC, RD, RE and RF have the values indicated in the description, and which are protein kinase inhibitors. The invention also relates to pharmaceutical compositions containing said compounds, and also to the use of said compounds to treat and/or prevent diseases related to aberrant protein kinase activity.
Bibliography:Application Number: CN201480046313