Fluorescence-SERS dual-mode super-resolution imaging probe and its preparation method and use method
The invention discloses a fluorescence-SERS dual-mode super-resolution imaging probe and its preparation method and use method. The fluorescence-SERS dual-mode super-resolution imaging probe is characterized in that 1, silica is coated with metal yolk-eggshell structure composite nanoparticles so th...
Saved in:
Main Authors | , , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
13.04.2016
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention discloses a fluorescence-SERS dual-mode super-resolution imaging probe and its preparation method and use method. The fluorescence-SERS dual-mode super-resolution imaging probe is characterized in that 1, silica is coated with metal yolk-eggshell structure composite nanoparticles so that the probe is prepared, 2, a Raman molecule with a fluorescence signal is added into the cavity of the probe so that fluorescence-SERS signal switching is realized, and 3, the shell surface of the silica is labeled through a specific targeting ligand for specific organelle super-resolution optical imaging. The fluorescence-SERS dual-mode super-resolution imaging probe realizes fluorescence-SERS dual-mode super-resolution optical imaging. |
---|---|
Bibliography: | Application Number: CN201510836925 |