Method for near-infrared online detection of effective components in carthamus tinctorius alcohol precipitation process

• Main Authors: ZHANG GUIPING, YAO XIAOQING, LI XIANJUN, SUN MINGZHEN, HU XIAOFENG, SUN CHANGHAI, ZHANG KUN, GAO JUNMIN
• Format: Patent
• Language: English
• Published: 14.10.2015
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention provides a method for near-infrared online detection of effective components in a carthamus tinctorius alcohol precipitation process. The method comprises steps of (1) carrying out near-infrared detection on a circulating pipeline on line; (2) collecting a near-infrared transmitted spectrum and an alcohol precipitation liquid sample of carthamus tinctorius alcohol liquid on line; (3) measuring various quality control index information (including hydroxysafflor yellow A and soluble solid content) by adopting a high-efficiency liquid chromatography and a drying and weighing method; (4) establishing a various quality control index model by adopting a partial least square method; and (5) analyzing the change trends of the various quality control indexes in the alcohol precipitation process on line by the established models. According to the method, near infrared spectroscopy is used for the carthamus tinctorius alcohol precipitation process, the mode of the combination of a circulating tank and an optical fiber probe is adopted, so that the online quantitative analysis of the hydroxysafflor yellow A and the soluble solid content in the carthamus tinctorius alcohol precipitation process can be realized, and basis and effective guide can be provided for the online control of the carthamus tinctorius alcohol precipitation process.