Omeprazole sodium compound prepared by particle process crystal product molecule assembly and shape optimization technique, and preparation of omeprazole sodium compound

The invention discloses an omeprazole sodium compound which is prepared by a particle process crystal product molecule assembly and shape optimization technique. The compound is an omeprazole sodium anhydrous compound, and has the characteristics of high purity, good flowability, low hygroscopicity...

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Bibliographic Details
Main Author TAO LINGGANG
Format Patent
LanguageEnglish
Published 30.09.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention discloses an omeprazole sodium compound which is prepared by a particle process crystal product molecule assembly and shape optimization technique. The compound is an omeprazole sodium anhydrous compound, and has the characteristics of high purity, good flowability, low hygroscopicity and good stability. In addition, the invention further discloses an omeprazole sodium medicine composition. The medicine composition comprises the following components in parts by weight: 20-60 parts of omeprazole sodium (by omeprazole), 1-2 parts of metal ion complexing agent and an appropriate amount of pH (potential of hydrogen) regulator. The omeprazole sodium medicine composition is simple in preparation process, requires no excipient, and has better stability than the former product.
Bibliography:Application Number: CN201510335075