Conjugates for the prevention or treatment of nicotine addiction

The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment...

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Main Authors MEHELIC PAUL ROBERT, DAVIS HEATHER LYNN, MERSON JAMES RICHARD, THORN JENNIFER MARIE, MCCLUSKIE MICHAEL JOHN, PARSONS ERIN KRISTEN, GERVAIS DAVID P, KOLHE PARAG ASHOK, STEAD DAVID ROBERT, BROWN ALAN DANIEL, BHATTACHARYA KESHAB, ANASTASIOU NICKOLAS, FINNEMAN JARI ILMARI, JONES LYN HOWARD, PRYDE DAVID CAMERON
Format Patent
LanguageEnglish
Published 30.09.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
Bibliography:Application Number: CN201510242271