Sulfur-based compound with anti-tumor activity and application thereof

The invention belongs to the technical field of medicine, and relates to a sulfur-based compound with anti-tumor activity, in particular to a sulfur-based compound containing 3(5)-substituted phenyl-5(3)-amido pyrazole segments, pharmaceutically acceptable salts and hydrates of the compound, a pharm...

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Bibliographic Details
Main Authors LIU DAN, ZHAO LINXIANG, YANG JINYU, WEN JIACHEN
Format Patent
LanguageEnglish
Published 30.09.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention belongs to the technical field of medicine, and relates to a sulfur-based compound with anti-tumor activity, in particular to a sulfur-based compound containing 3(5)-substituted phenyl-5(3)-amido pyrazole segments, pharmaceutically acceptable salts and hydrates of the compound, a pharmaceutical composition using the compound as an active ingredient, and application of the sulfur-based compound in preparation of a histone deacetylase inhibitor and treatment and/or prevention of cancers. The structure of the compound as well as the pharmaceutically acceptable salts and hydrates thereof is shown in the Specification, and the variables are described in the claims and the Specification.
Bibliography:Application Number: CN201510328564