Method for qualitative and quantitative analysis of titanium dioxide or/and zinc oxide nanoparticles in cosmetic

• Main Authors: XIANG DAPENG, WANG SUJUAN, WEI XIAOQUN, LUAN TIANGANG, LIU HONGTAO, GONG LI
• Format: Patent
• Language: English
• Published: 16.09.2015
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention discloses a method for qualitative and quantitative analysis of titanium dioxide or/and zinc oxide nanoparticles in a cosmetic. The method includes: using ethyl acetate and ethanol to conduct dissolution and centrifugation treatment on the cosmetic to remove most organic components, performing drying, then conducting TEM, XRD and XPS analysis on the sample, observing the shape through TEM to obtain the particle size distribution so as to confirm whether a nano-material is added, performing XRD analysis to obtain the phase components and structure of the additive, and performing XPS to obtain the chemical form of elements; then combining ICP-OES quantitative determination to obtain the element content, thereby obtaining the content and morphological structure information of nano-components in the sample. The method can be used for detection of titanium dioxide or/and zinc oxide nanoparticles in cosmetics, and has the characteristics of small nanoparticle loss, accurate result, and safe operation process. Also the method provided by the invention has wide detection application range, is not only suitable for treatment of sun cream samples, and is also applicable to liquid foundations, compact powder and other sunscreen and whitening products.