Antitumor medicine

The invention discloses an antitumor medicine with jervine or a pharmaceutically acceptable salt thereof as an effective component. Experiments prove that jervine is a very effective Hedgehog signal pathway inhibitor, and a result of experiments of 3 human tumor xenograft models shows that jervine i...

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Bibliographic Details
Main Author GONG XIANCHANG
Format Patent
LanguageEnglish
Published 16.09.2015
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:The invention discloses an antitumor medicine with jervine or a pharmaceutically acceptable salt thereof as an effective component. Experiments prove that jervine is a very effective Hedgehog signal pathway inhibitor, and a result of experiments of 3 human tumor xenograft models shows that jervine is an effective antitumor and can strongly inhibit the in vivo growth of human lung cancer, pancreas cancer and basal cell cancer cells. Jervine has huge potential to be developed to wide-spectrum antitumor new drugs.
Bibliography:Application Number: CN201410088721