Optically-active diazabicyclooctane derivative and method for manufacturing same

Provided are an optically active diazabicyclooctane derivative defined by formula (F) below, which is useful as a pharmaceutical intermediate for -lactamase inhibitor, and a process for preparing the same. In formula (F) above, R 1 represents CO 2 R, CO 2 M, or CONH 2 , wherein R represents a methyl...

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Bibliographic Details
Main Authors OKUE MASAYUKI, ABE TAKAO, SAKAMAKI YOSHIAKI
Format Patent
LanguageEnglish
Published 09.09.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Provided are an optically active diazabicyclooctane derivative defined by formula (F) below, which is useful as a pharmaceutical intermediate for -lactamase inhibitor, and a process for preparing the same. In formula (F) above, R 1 represents CO 2 R, CO 2 M, or CONH 2 , wherein R represents a methyl group, a tert-butyl group, an allyl group, a benzyl group, or a 2,5-dioxopyrrolidin-1-yl group, and M represents a hydrogen atom, an inorganic cation, or an organic cation; and R 2 represents a benzyl group or an allyl group (img file='DDA0000708486690000011. TIF' wi='376' he='1143' /).
Bibliography:Application Number: CN201510212878