Preparation method and application of L-ornithine succinate neutral salt

• Main Authors: SHI NAN, WAN HONGGUI, DING JUNFENG, WAN MIAO
• Format: Patent
• Language: English
• Published: 12.08.2015
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the field of the medicine chemical industry, and discloses a preparation method and application of an L-ornithine succinate neutral salt. The method comprises the following steps: preparing a free L-ornithine aqueous solution at first, adding succinate powder, crystals or solution into the aqueous solution, stirring for reaction to obtain an L-ornithine succinate neutral salt solution, and then separating out the L-ornithine succinate neutral salt in the form of crystals. The method is simple and feasible, is low in production cost and high in product yield and purity, and can be used for performing industrial popularization, and the L-ornithine succinate neutral salt can be used for preparing medicaments for treating diabetes and various antidotes.