CO-CRYSTALS OF TRAMADOL AND COXIBS

The invention provides co-crystals of tramadol and coxibs. The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the tre...

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Bibliographic Details
Main Authors TESSON NICOLAS, SALAMAN CARLOS RAMON PLATA
Format Patent
LanguageEnglish
Published 05.08.2015
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides co-crystals of tramadol and coxibs. The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, the co-crystal is (rac) - tramadol. HcI - celecoxib (1:1).
Bibliography:Application Number: CN201510128029