Benzamide compound and applications thereof

The present invention discloses applications of a benzamide compound having a structure represented by a formula (I) or a pharmaceutically acceptable salt or a stereoisomer or a prodrug molecule in preparation of drugs for diseases requiring application of complete or partial exciting or antagonisti...

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Main Authors ZHANG YANMEI, LIU JIANQI, LU XIN, TAN XIAOCHU, MICKY D. TORTORELLA, TU ZHENGCHAO, LIAO JINXI, GUAN JIANTONG, GUO YIPING, LU YONGZHI, HE JUFANG
Format Patent
LanguageEnglish
Published 15.07.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention discloses applications of a benzamide compound having a structure represented by a formula (I) or a pharmaceutically acceptable salt or a stereoisomer or a prodrug molecule in preparation of drugs for diseases requiring application of complete or partial exciting or antagonistic action to stimulate cholecystokinin receptors during treatment or prevention treatment, wherein R1, R2, R3 and R4 are respectively and optionally 0, 1 or 2 groups selected from OH, F, Cl, Br, I, Me, NO2, OMe, OAc, Ac, OBz, CF3, tBu, OiPr, Et, OEt, NH2, NHBu, COOH, COOMe, CH2N(CH2)2O, CN, N(CH3)3I, 1H-1,2,4-triazole, OCH2CH2OAc, and OCH2CH2OH. The formula (I) is defined in the instruction.
Bibliography:Application Number: CN2014113373