An early-stage screening kit for diabetic nephropathy, a biomarker detecting method and applications

An early-stage screening kit for diabetic nephropathy is disclosed. The kit comprises detection agents. The detection agents comprise a first detection agent, a second detection agent, a third detection agent and a fourth detection agent. The solute of the first detection agent is a first podocalyxi...

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Bibliographic Details
Main Authors KHRYSTYNA PRONYUK, OLENA KULIESH, ZHU KONGLIN, ZHANG JUNRAN, GU DONGFENG, PODOBED IVAN, YANG YI, ZHANG GUANJING, LUCA MUSANTE, LIU YAOFENG, SHI JIANGBO
Format Patent
LanguageEnglish
Published 08.07.2015
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:An early-stage screening kit for diabetic nephropathy is disclosed. The kit comprises detection agents. The detection agents comprise a first detection agent, a second detection agent, a third detection agent and a fourth detection agent. The solute of the first detection agent is a first podocalyxin antibody. The solute of the second detection agent is a first IV type collagen antibody. The solute of the third detection agent is a first liver-type fatty acid-binding protein antibody. The solute of the fourth detection agent is a first neutrophils gelatinase-associated lipocalin antibody. The kit adopts podocalyxin, IV type collagen, liver-type fatty acid-binding protein and neutrophils gelatinase-associated lipocalin as biomarkers, and can provide assisted determination for renal injury according to actual detection results, thus providing assistance for differentiating early-stage diabetic nephropathy.
Bibliography:Application Number: CN20151130214