TNF -alpha modulating benzimidazoles

A series of benzimidazole derivatives, being potent modulators of human TNFalpha activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive diso...

Full description

Saved in:
Bibliographic Details
Main Authors LOWE MARTIN ALEXANDER, GALLIMORE ELLEN OLIVIA, PORTER JOHN ROBERT, BROOKINGS DANIEL CHRISTOPHER, SELBY MATTHEW DUNCAN, LECOMTE FABIEN CLAUDE, NORMAN TIMOTHY JOHN, ZHU ZHAONING, FOLEY ANNE MARIE, HORSLEY HELEN TRACEY, CALMIANO MARK DANIEL, REUBERSON JAMES THOMAS, SHAW MICHAEL ALAN, JOHNSON JAMES ANDREW, HUTCHINGS MARTIN CLIVE, QUINCEY JOANNA RACHEL, KROEPLIEN BORIS
Format Patent
LanguageEnglish
Published 18.03.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:A series of benzimidazole derivatives, being potent modulators of human TNFalpha activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
Bibliography:Application Number: CN201380037400