2,6-bis-nitrogenous substituted purine derivative as well as preparation method, pharmaceutical composition and application thereof

The invention provides a 2,6-bis-nitrogenous substituted purine derivative with a structure as shown in a formula (I) or pharmaceutical salt thereof or a hydrate thereof as well as a preparation method and an application thereof. The compound provided by the invention has the characteristics of low...

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Main Authors XU YONGMEI, WANG JUN, XIAO SEN, CAI JINNA, MAO WEI, WU GUOFENG, CHEN CHUNLIN, LIN XIAOQIN, LYU LILI, WU ZHANGGUI
Format Patent
LanguageEnglish
Published 18.03.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides a 2,6-bis-nitrogenous substituted purine derivative with a structure as shown in a formula (I) or pharmaceutical salt thereof or a hydrate thereof as well as a preparation method and an application thereof. The compound provided by the invention has the characteristics of low toxicity, wide anti-cancer spectrum, high anti-cancer activity, good stability and the like.
Bibliography:Application Number: CN201410417725