PEPTIDES INHIBITING MATURATION OF T-LYMPHOCYTES AND ACTIVITY OF MACROPHAGES, PHARMACEUFICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARINY SAME

The invention relates to novel peptides of by formulae (1) to (20): Arg-Lys(Chc)-Asp-Val (1) Arg-Lys(Chc)-Asp (2) Arg-Sar-Asp-Val (3) Arg-Sar-Asp (4) Orn-Lys-Asp-Val (5) Orn-Lys-Asp (6) Arg-Lys-Aad-Val (7) Arg-Lys-Aad (8) [Arg-Lys-Asp-NH-CH2-]2 (9) [Arg-Lys-Asp-Val-NH-CH2-]2 (11) [Arg-Lys-Asp- @ys-N...

Full description

Saved in:
Bibliographic Details
Main Authors LAJOS KISFALUDY, OLGA NYEKI, ISTVAN SCHON
Format Patent
LanguageEnglish
Published 25.07.1990
Edition5
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention relates to novel peptides of by formulae (1) to (20): Arg-Lys(Chc)-Asp-Val (1) Arg-Lys(Chc)-Asp (2) Arg-Sar-Asp-Val (3) Arg-Sar-Asp (4) Orn-Lys-Asp-Val (5) Orn-Lys-Asp (6) Arg-Lys-Aad-Val (7) Arg-Lys-Aad (8) [Arg-Lys-Asp-NH-CH2-]2 (9) [Arg-Lys-Asp-Val-NH-CH2-]2 (11) [Arg-Lys-Asp- @ys-NH2]2 (12) Lys-Ser-Lys-Leu (13) Ser-Lys-Leu (14) Ser-Ser-Ser-Thr (15) Lys-Glu-Thr (16) Lys-Thr-Glu-Thr (17) Pro-Lys-Leu-Thr (18) Lys-Lys-Thr-Glu (19) Lys-His-Leu-NH2 (20) and their preparation. The novel peptides are useful for therapy, where a general suppressing action on the function of the immune system is desired.
Bibliography:Application Number: CN19891009713