IL-17RA-IL-17RB antagonists and uses thereof

The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as v...

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Bibliographic Details
Main Authors BUDELSKY ALISON L, COMEAU MICHAEL R, TOCKER JOEL E
Format Patent
LanguageChinese
English
Published 19.11.2014
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as various methods of use.
Bibliography:Application Number: CN201410242489