IL-17RA-IL-17RB antagonists and uses thereof
The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as v...
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Main Authors | , , |
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Format | Patent |
Language | Chinese English |
Published |
19.11.2014
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as various methods of use. |
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Bibliography: | Application Number: CN201410242489 |