Polyglycosaminoglycan polypeptide complex iodine composite system solution and preparation method thereof

The invention discloses a polyglycosaminoglycan polypeptide complex iodine composite system solution which is a network system solution using chitosan, epsilon-polylysine and iodine as main active components and poloxamer as a stabilizing agent and having sterilization and restoration functions. A p...

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Bibliographic Details
Main Authors NIE KAIPIN, ZHENG MAOXIN, CHEN JIE, HUANG CHANGPING
Format Patent
LanguageChinese
English
Published 23.07.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention discloses a polyglycosaminoglycan polypeptide complex iodine composite system solution which is a network system solution using chitosan, epsilon-polylysine and iodine as main active components and poloxamer as a stabilizing agent and having sterilization and restoration functions. A preparation method for the solution comprises preparation of a functional complexation carrier, an assistant dissolving and emulsification system and a complex iodine system and organic combination of the above-mentioned carrier and the systems. According to the invention, a chitosan iodine complex, an epsilon-polylysine iodine complex and free iodine in the system are substances with bactericidal activity, and chitosan iodine can promote wound healing; poloxamer has a solubilizing function and is the stabilizing agent for iodine; potassium iodide and sodium iodide can stabilize elemental iodine and balance physiological saline ions. The solution provided by the invention has good killing effects on Gram-positive ba
Bibliography:Application Number: CN2014189322