Production method and application of coding suspension microchip for joint detection of multiple tumor markers

• Main Authors: KONG YUNHUA, ZHENG KEXIAO, LI JIONG, YAN LINGCHEN
• Format: Patent
• Language: Chinese; English
• Published: 26.03.2014
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention discloses a production method and application of a coding suspension microchip for joint detection of multiple tumor markers. The production method comprises the following steps: providing a coding suspension microchip base body comprising a transparent substrate and a plurality of non-transparent plane microstructures distributed on the transparent substrate and used as graphic identification codes; and providing antibody pairs corresponding to more than ten tumor markers, connecting an antibody in each antibody pair to the transparent substrate as probe molecule, and connecting the other antibody with a marking material. The coding suspension microchip can be used for detecting multiple tumor markers. The production method of the coding suspension microchip is simple and the cost is low; the coding suspension microchip can detect more than ten tumor markers in a biological sample at the same time or select several for co-check; the detection method is convenient and fast, the detection result