Method for the preparation of high-purity pharmaceutical intermediates

• Main Authors: BARTHA FERENC LORANT, RUZSICS GYOERGY, VOLK BALAZS, BAGYINSZKI GABOR, IMRE JANOS, KOVANYINE LAX GYOERGYI, NAGY KALMAN, SIPOS EVA, BARKOCZY JOZSEF, KESZTHELYI ADRIENN, KRASZNAI GYOERGY, SIMIG GYULA, MOROVJAN GYOERGY
• Format: Patent
• Language: Chinese; English
• Published: 11.09.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention is related to intermediates useful in the preparation of pharmceutically acceptable salts of (+)-7-[4-(4- fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)- pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparatio...